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Huntexil® (pridopidine)

 

Huntexil® (pridopidine, previously designated ACR16) is a dopaminergic stabiliser which NeuroSearch is evaluating in a clinical Phase III programme in Huntington’s disease with the aim of registering and marketing the product as one of the first specific treatments for patients suffering from this severe disease. Huntington’s disease is a relatively rare hereditary neurodegenerative genetic disorder leading to the degeneration of brain tissue. In several studies Huntexil® has demonstrated highly promising effects on a number of the very disabling symptoms related to the disease.

 

 

 

Click below for further details:

 

  

Pridopidine - A dopaminergic stabiliser 

 

- Mechanism of action

Development programme in Huntington's Disease

 

- the MermaiHD study
- the HART study
- Coimpassionate use of Huntexil®

- Huntington’s disease
 

Events

 

 

 



Latest programme presentations and posters

 

 

November 2009 - HSG 2009 in Baltimore:

 

Validation of the modified motor score (mMS): a subscale of the Unified Huntington’s Disease Rating Scale (UHDRS) motor score

 

Pridopidine (ACR16) in Huntington’s disease: an update on the MermaiHD and HART studies

 

The Huntington Self-Assessment Instrument (HSAI): a comprehensive and specific tool to measure the burden of Huntington’s disease

 

Euro-HDB – the first large, comprehensive European study on the burden of Huntington’s disease

 

Pharmacology of the dopaminergic stabilizer pridopidine (ACR16)

 

Programme news

 

30 June 2010 - New article published in The Lancet reveals massive underestimation of the prevalence of Huntington’s disease in the UK

28 April 2010 - NeuroSearch A/S announces the results of additional assessment and analysis of data from the Phase III MermaiHD study with Huntexil® in Huntington's disease

8 March 2010 - NeuroSearch announces new findings from the MermaiHD Phase III study supporting potential disease modifying properties of Huntexil®

3 February 2010 - NeuroSearch announces positive top-line results from Phase III Huntexil® study in Huntington's disease (the MermaiHD study)

 

15 September 2009 - NeuroSearch presents supportive data on the novel therapy HuntexilTM at the World Congress on Huntington’s disease

 

25 August 2009 - NeuroSearch achieves approval for HuntexilTM as brand name for pridopidine – a novel therapeutic approach for Huntington’s disease

 

Download annual reports

 

Årsrapport 2009
Annual report 2009
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